tb 500 fragment (17 23) 10mg
tb 500 fragment (17 23) 10mg

TB-500 FRAGMENT (17-23) 10MG

$100.00

TB-500 Fragment (17-23) is a research peptide consisting of a short amino acid sequence derived from the actin-binding region of Thymosin Beta-4. It has been shown in preclinical studies to regulate cell migration, angiogenesis, and cytoskeletal organization through modulation of actin polymerization. This fragment is used in experimental research investigating wound repair, tissue remodeling, and peptide-mediated regenerative signaling mechanisms.

For research use only. Not for human consumption.

References:
Goldstein AL et al., Ann NY Acad Sci, 2007 1112:148–154
Huff T et al., J Mol Biol, 2001 312(3):593–606
Malinda KM et al., FASEB J, 1999 13(14):2106–2114

TB-500 Fragment (17-23), also called fequesetide or (17) (LKKTETQ) (23), represents the smallest portion of the thymosin beta-4 molecule that retains the larger protein’s active binding domain. Research indicates that this synthetic derivative of thymosin beta-4 is capable of binding to actin, the molecule inside of cells that is responsible for improved cell structure, movement (a.k.a. migration), and replication. By altering the function of actin in cells, TB-500 Fragment (17-23) has been shown to modulate the immune response and alter cell migration patterns. This can lead to large-scale changes in tissue/organ structure and function. In animal models, these changes have been shown to accelerate wound healing, decrease inflammation, promote blood vessel growth, reduce scar formation, improve musculoskeletal function, and help to slow or reverse the course of certain disease conditions.

Category:

TB-500 Fragment (17-23) 10mg is a short synthetic peptide derived from Thymosin Beta-4 (TB-500), consisting of a specific 7-amino acid sequence within the larger 43-amino acid molecule. This fragment is designed to retain the key functional properties of TB-500, particularly its role in tissue repair, cellular migration, and wound healing, while offering enhanced stability and easier handling for research purposes. The peptide has been studied primarily in preclinical settings for its potential to promote regeneration of muscles, tendons, ligaments, and other soft tissues by supporting actin filament formation and modulating inflammatory responses.

At a 10mg dosage, TB-500 Fragment (17-23) is typically supplied as a lyophilized powder intended for research or experimental use and requires proper reconstitution before application. Early studies suggest it may accelerate tissue repair, improve flexibility, and aid recovery from injuries by enhancing cellular migration and angiogenesis in damaged areas. While it shows promise in preclinical models, the fragment is not approved by major regulatory authorities for clinical or therapeutic use, and its long-term effects in humans are not fully understood. As a biologically active peptide that influences critical regenerative pathways, professional supervision and adherence to research protocols are essential to ensure safety, proper dosing, and accurate assessment of its effects.

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